The phrase "a much higher affinity for" is correct and usable in written English.
It can be used in contexts discussing the strength of attraction or preference between entities, such as in scientific or comparative discussions.
Example: "The new drug shows a much higher affinity for the target receptor compared to the previous version."
Alternatives: "a significantly greater affinity for" or "a considerably stronger affinity for".
Hemoglobin has a much higher affinity for carbon monoxide than for oxygen.
Due to negative selection, naturally occurring TCRs bind self (tumor) peptides with low affinity and have a much higher affinity for foreign antigens.
The results for reduction of 4′-chloroacetophenone showed that the enzyme had a much higher affinity for NADH than NADPH.
Despite NMDARs having a much higher affinity for glutamate than AMPARs, quantal release resulted in similar occupancy levels in both receptor types.
S. cerevisiae take up xylose through the family of hexose transporters, which have a much higher affinity for glucose than xylose (Cai et al. 2012).
If a structure is predicted to have a much higher affinity for the target than it actually does, the cost to a lead optimization program is limited to the synthetic resources wasted on that particular structure.
With time these complexes and precipitates are reordered to give a much higher affinity of iron (hydr oxides for phosphate.
When C4F6 is presented with denatured protein on immunoblots, a much higher affinity of the antibody for SOD1 containing the D-K-D-A sequence at 90 93 (as would be the case for the G93A variant) over D-A-D-G (for WT hSOD1) was revealed.
The Ki value for 5-ghmC is 10-fold lower than the Km value for 5-hmC (Tables 1 and 2), suggesting a much higher affinity of the β-GT enzyme for 5-hmC.
Whereas CTLA-4 has a much higher affinity than CD28 for their ligands, it is not expressed constitutively on naive T cells and is mostly localized intracellularly.
But even small amounts of CTLA-4 could potentially inhibit T cell activation when CD80/CD86 molecules are expressed at low levels because CTLA-4 has a much higher affinity than CD28 for CD80/CD86 [ 2]; moreover, it is preferentially localized in lipid rafts [ 24].
