The phrase "a mouse model characterized" is correct and usable in written English.
It can be used in scientific or research contexts when describing a specific type of mouse model that has particular traits or features.
Example: "In our study, we utilized a mouse model characterized by a high susceptibility to cancer."
Alternatives: "a mouse model defined by" or "a mouse model distinguished by".
However, these mechanisms have been proposed to explain the recent observation that a pan-PPAR agonist, bezafibrate, was able to correct the COX defect, ameliorate motor impairment, and prolong life span, in MLC1F-Cox10 −/−, a mouse model characterized by muscle-selective ablation of Cox10, a heme a biosynthetic enzyme.
Samuele De Minicis (Università Politecnica delle Marche, Ancona, Italy) demonstrated the role of fibrosis as a cofactor in a new mouse model characterized by the evolution of NASH to liver cancer.
Using a transgenic mouse model characterized by CNS hypermyelination, we show that larger myelin content results in greater severity of experimental autoimmune encephalomyelitis attributable to an increased number of microglia within the hypermyelinated brain.
To assess the potential role of transforming growth factor beta (TGF-β) overactivity in driving these cardiovascular abnormalities, we studied a novel transgenic mouse model characterized by ligand-dependent activation of TGF-β signaling in fibroblasts.
The potential role of Tregs in modulating bone homeostasis in a FoxP3-overexpressing mouse model characterized by increased numbers of Tregs has been demonstrated; these mice showed high bone volume and low osteoclast numbers, with no change in bone formation showing partial attenuation of bone loss [ 43].
The humanized mouse model characterized in this paper may facilitate the study and understanding of the functions of the human CYP2C enzymes.
As in human, the phenotype of the deletion mouse model depends on the parental origin: paternal or maternal inheritance of the Tg-deletion, respectively, results in the TgPWS mouse model characterized by severe neonatal hypoglycemia and early lethality [ 9] or in TgAS mice with a mild neurobehavioral phenotype and late onset obesity [ 7].
Among AD animal models, TgCRND8 mice showed a more extensive spectrum of synaptic alterations compared to other AD mouse models, characterized by mutations only in the APP gene (APP23 and Tg2576 mice).
We tested this hypothesis on three recombinant mouse models characterized by defective cytochrome c-oxidase (COX) activity: a knockout (KO) mouse for Surf1, a knockout/knockin mouse for Sco2, and a muscle-restricted KO mouse for Cox15.
Transgenic mouse models characterized by conditional expression of the simian virus 40 T antigen oncogene in postmitotic neurons clearly presented a neurodegenerative phenotype, consequence of forced cell cycle activation [ 32].
