Watch the mouse in action below.
The story goes that as soon as he saw what would become the modern-day mouse in action, Jobs began pacing the room excitedly, and when he finally couldn't contain himself any longer, he said, 'you're sitting on a gold mine'.
Yao, J. J. et al. High-speed label-free functional photoacoustic microscopy of mouse brain in action.
Yao, J Wangg, L; Yang, J-M; Maslov, KI; Wong, TTW; Li, L; Huang, C-H; Zou, J Wangg, LV, High-speed label-free functional photoacoustic microscopy of mouse brain in action., Nature Methods, vol 12 no.
In addition, it was shown that this characteristic appeared to translate into enhanced which duration of action in a mouse model of bronchonstriction.
The exciting new findings of Ozcan et al. indicate that chemical chaperones improve glucose tolerance and insulin action in a mouse model of type 2 diabetes.
Targeted delivery of anti-inflammatory cytokines potentiates their anti-arthritic action in a mouse model of arthritis.
Next we turned to another potential candidate, the GABAA receptor, since some reports in the literature suggest that avermectin can bind to the GABAA receptor in rat brain membranes or cultured cerebellar neuronal assays (Pong et al., 1982; Huang and Casida, 1997), and avermectin exhibits an anticonvulsant action in a mouse seizure model (Dawson et al., 2000).
This finding is consistent with a recent study showing a significant increase in RGC spontaneous firing of action potentials in a mouse model of microbead-induced ocular hypertension.
A high-resolution images shows neurons in action as the mouse navigates the virtual-reality system.
These results indicate that GSL inhibition in obese mice primarily results in an increase in insulin action in the liver, and suggests that GSLs may have an important role in hepatic insulin resistance in conditions of obesity.
