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It therefore has advanced the field of constructing phenotypes at a more wild space as compared with the rational tools [ 5].
Only apply a little red to the outer edge of your eyelid, or brush it out in streaks right past your eyes to create a more wild, crazy look.
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We next wanted to study the role of the GLS in gurken RNA localization and gene function within the context of a more wild-type transcript.
This is particularly compelling in cases where pax1-1 confers a more wild-type phenotype on axr3 mutants, despite having the opposite effect in a wild-type background.
Treatment with Pip6e-PMO led to widespread restoration of the dystrophic proteome towards a more wild-type expression profile (Fig. 2B).
Suppressors were selected if the eye was larger, less rough and had a more wild-type-like ommatidial organization than control eye phenotypes.
We also observed a more wild-type root hair phenotype in the double mutant than was observed in either of the single-mutant parents.
This suggests that the crosses exhibiting a more wild-type phenotype had lower survival; this trend fits with observations on the same crosses within a semi-natural environment designed for competitive interactions among strains (Tymchuk et al. 2007).
Upon ubiquitously overexpressing FL- clu or CLUH using daughterless (da) GAL4, we found that the mitochondria were much more dispersed and had a more wild-type pattern of distribution (Fig. 1J,K).
Co-depletion of both WEE-1.3 and CDK-7 suppressed the precocious oocyte maturation phenotype exhibited by depletion of WEE-1.3 alone and returned the gonad to a more wild-type expression pattern, with the three to four most proximal oocytes being pH3-positive and Nop1p-negative.
Under the conditions used to characterize the SeCobAF91W/W93F variant kinetically (i.e., in the absence of glycerol and at 298 K), the enhanced thermal motion of residues 91 and 93 may cause the active site to adopt a more wild-type-like conformation, resulting in kcat and KM values similar to those of SeCobAWT.
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