On the one hand, they can undergo bimolecular interactions with several proteins (enzymes) or, on the other hand, perturb a larger membrane area thus activating a series of proteins in a more unspecific manner.
Although unusual fatigue and irritability as unspecific mood changes are also taken into consideration, to the best of our knowledge, no investigation to date has studied whether a more unspecific symptom picture beyond the known premonitory signs of an acute hyperglycaemia is indicative for the development of T2DM several years before the point of clinical recognition.
From measuring non-cognitive facets within the problem-solving process, a better ecological validity than from administering more unspecific retrospective self-report questionnaires that are separated from context, is assumed.
We show here that specific downregulation of ROCK2 in RGCs is sufficient to promote neurite outgrowth to a similar extent as reported before for the more unspecific ROCK inhibitors.
Therefore, the modules (between the two conditions), with an increased number of shared genes tend to be more unspecific.
(Female17 FGD5) There may be more unexplored diseases affecting women, or, well, more unspecific symptom patterns that we do not really have an understanding of… But it's very easy when you feel frustrated and want to help that you think, "Well, but there must be some medicine for this", and there is usually something you can prescribe.
There may be more unexplored diseases affecting women, or, well, more unspecific symptom patterns that we do not really have an understanding of… But it's very easy when you feel frustrated and want to help that you think, "Well, but there must be some medicine for this", and there is usually something you can prescribe.
The initial prodromal state of psychosis (IPS) is defined as an early disease stage prior to the onset of overt psychosis characterized by sub-threshold or more unspecific psychiatric symptoms.
The more kinds of abundant proteins are depleted, the more unspecific bounded proteins may loose [ 29].
This could be associated with more unspecific symptom reporting in general, including reporting of diffuse regional pain.
Thus, in the presence of depressive symptoms, pain becomes more unspecific so the ability of pain complains to allow the identification of patients with radiographic OA is lower.
