Sentence examples for a more substantial problem from inspiring English sources

However, label noise may be a more substantial problem in the understanding of pathways in more advanced organisms.

The other, more substantial problem is her cravenness towards Russia.

Other first generation tau tracers, such as [18F]THK5351 ([18F]GE216) [38] 38], have shown even more substantial problems with a large amount of off-target binding to MAO-B that also compromises the interpretation of cortical regions [35].

Many critics (including me) argued at the time that this winking, "Leaned In" persona obscured Clinton's more substantial problems and anti-feminist attributes, like being a war hawk and supporting disastrous welfare-to-work programmes.

The inspectors will also be on the lookout for more substantial problems, like homeless people in need of aid, the mayor said.

A more significant problem is saturation.

The work for the course will consist primarily of two problem sets, a short reaction paper, and a more substantial project.

Does a more expensive cocktail warrant a more substantial tip?

Now she's back, but in a more substantial role.

For a more substantial salad, top with crispy bacon – delicious!

Orpheus might also have chosen a more substantial piece.