A preliminary positive test result requires confirmation by a more specific test, typically the Western blot.
For example, many screening programmes use tests with less than perfect Sp if this gives a high Se and then use a more specific test to confirm any positive animals.
A more specific test for ABCA1 function is provided by cells from ABCA1−/− mice and from Tangier patients homozygous for mutations that disrupt expression of the human ABCA1 gene.
A more specific test, such as the indirect immunofluorescence test, should clarify this uncertainty (18 ).
Tests positive for IgM were further analysed with a more specific test (IDEIA, Dako).
This permitted a more specific testing of the influence of ROUND.
A more specific test would be to compare the time course of active Rac1 in the patch with Nadrin2 levels.
As a more specific test will produce fewer positive results than a less specific test with identical sensitivity, doubts may arise as to the sensitivity of the more specific test.
The horizontal grid test examines the deficits in descending fine motor control and therefore represents a more specific test to assess CST integrity.
The lack of a more specific test has been a real obstacle to the evaluation of the prevalence and economic impact of CCPP worldwide.
Such experimental analyses move beyond descriptive data obtained by questionnaire or interviews, and provide a more specific test of hypotheses than is possible from treatment manipulations.
