Sentence examples similar to a more significant mutation from inspiring English sources

There appears to be a more significant association of this mutation with the RF-negative phenotype.

The ratio of the per-site rate of recombination to the per-site rate of mutation (c/μ) in all genes was less than one, indicating that mutation plays a more significant role in producing novel genetic combinations than recombination and is, therefore, the major force driving the evolution of these viral populations [see [ 18]].

These findings establish de novo germline mutation as a more significant risk factor for ASD than previously recognized.

The rarity of germline EPHB2 mutations supports a more significant role for EPHB2 in colorectal tumor progression rather than in tumor initiation.

As predicted by the structural data, site 2 mutations had a more significant effect on signaling in the Wnt reporter assay.

PY1 has a more significant role in nuclear import than PY2, since mutation of PY1 results in a more significant defect than mutation of PY2.

One major finding of the paper by Bild et al. was that clustering patients into six groups based on all five mutations together gave a more significant differential prognosis.

The half-life of Fc-fusions is typically shorter than intact Abs (1 2 weeks against 3 4 weeks; Suzuki et al, 2010), and so it might be expected that equivalent mutations would make a more significant effect on the half-lives and overall efficacy of Fc-fusions than mAbs.

Reductions in red cell counts, hematocrit and hemoglobin concentrations suggested a more significant defect in hematopoiesis and beyond the scid mutation (Qing et al., 2012).

A more significant problem is saturation.

The frequency of aberrant hypermethylation has been used to suggest that epimutations might be more significant than mutations in carcinogenesis [ 26], but this is difficult to reconcile with evidence suggesting that relatively few mutations are likely to be required for carcinogenesis [ 34, 73].