Sentence examples for a more severe issue from inspiring English sources

A more severe issue in terms of (research) ethics is that of the missing "informed consent" in SMA, comprehensively dealt with in Krieger, Grubmüller et al. [36].

An even more severe issue, however, stems from the fact that exact promoter regions are unknown practically for all the genes.

The perception that one can readily take precautions against the sun may explain why it is not viewed as a more severe health issue by outdoor workers.

I'm incredibly reluctant to prescribe an antidepressant for someone under the age of 18, as more severe issues should not be managed in primary care, but with the obstacles in place and when presented with extreme distress, it can sometimes feel like the only option to help in the interim.

Afraid that he's hurt his leg, Travis rushes to the hospital, only to find that he in fact is struggling with far more severe issues.

Our findings provide additional information on this issue: a more severe chondral lesion is more likely to lead to metabolic changes, which may be associated with a poorer prognosis.

The N.C.A.A. said it was issuing a more severe penalty because Mulkey was a repeat offender.

By 9 50 a.m., the university issued a more severe warning by e-mail, phone and loudspeaker.

An increased penetration into diseased skin would require a more severe scrutiny of local and systemic biosafety issues.

The Met Office has issued yellow warnings for various parts of England and Scotland and a more severe amber warning for the North West of England.

A more severe form of B.P.H. is not always benign.