The phrase "a more sensitive endpoint" is correct and usable in written English.
It can be used in contexts where you are discussing a more delicate or responsive measure or target in a particular situation, such as in scientific research or data analysis.
Example: "In our study, we decided to focus on a more sensitive endpoint to better capture the effects of the treatment."
Alternatives: "a more delicate measure" or "a more responsive target."
Other end-points, such as oxygen transport variables, D O2, cardiac index, V O2, lactate, base deficit, and mucosal gastric pH, are all more sensitive endpoints of cellular resuscitation [ 65].
These results demonstrated that population density was a much more sensitive endpoint for population level risk assessments.
This suggests that cholinesterase inhibition is at least a 10-fold more sensitive endpoint than pup mortality for dietary exposures.
However, what is now needed is a systems-level approach investigating more subtle yet potentially more significant impacts of nanomaterial exposure in agricultural systems, including the use of a range of more sensitive endpoints that can mechanistically characterize toxicity.
This so-called "CLARITY-BPA" study also represents a paradigm that could easily incorporate a strategy to validate new and more sensitive endpoints into guideline studies [ 39].
Standard test data are still preferred and recommended for regulatory environmental risk assessments of pharmaceuticals even though data generated by non-standard tests could improve the scientific basis of risk assessments by providing relevant and more sensitive endpoints.
For PCBs, risk was first assessed at high doses in adults, but later more sensitive endpoints were detected at lower doses and in earlier life-stages.
These two points underline the need to develop more sensitive endpoints better able to demonstrate the true benefit of antineoplastic treatments, particularly as targeted therapies may moderately increase response rates but also improve the quality of the response and reduce the risk of progression.
Thus, using an endpoint of radiologically confirmed alveolar pneumonia (RCAP) can provide a more sensitive, but less specific, diagnosis of bacterial pneumonia that can be used to monitor the impact of pneumococcal conjugate vaccines (PCVs) on disease incidence (2, 3 ).
