Sentence examples similar to a more profound failure from inspiring English sources

The NRL showed an even more profound failure of culture, with players variously charged for assault, in court on sexual assault charges, and charged with distributing sexual images without consent.

34 Nevertheless, bendamustine should be used with caution in patients with mild hepatic dysfunction and mild to moderate renal impairment, bendamustine should be avoided with more profound failure (CrCL < 40 mL/min, AST or ALT > 2.5 upper limit of normal (ULN), or total bilirubin >1.3 ULN) as limited studies have been executed in these sittings.

Mr Turner argued that the regulatory shortcomings, shared by both the FSA and the Bank of England, were rooted in a more profound intellectual failure to grasp the risks that were building up in global finance.

More profoundly, it is a mistake to conflate whatever legal wrongdoing the president and those around him may have engaged in with Trump's even more profound failures of morality and leadership.

Others said Obama's failure to reap any dividends from his rapprochement with Russia was due to a more profound conceptual weakness: his failure to define America's role in the 21st century.

On the other hand, patients with chronic renal failure due to graft failure have a poorer renal function at the time of dialysis reinitiation, and a more profound anaemia [ 7].

The article offered a more profound explanation.

Does it make one a better -- a more profound -- person?

I could imagine a more profound or interpretively charged performance.

Or is it indicative of a more profound nationwide problem?

Eventually it will have a more profound effect.