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The phrase "a more practical substitute" is correct and usable in written English.
You can use it when discussing alternatives that are more feasible or useful in a given context.
Example: "In this recipe, we found that using Greek yogurt is a more practical substitute for sour cream."
Alternatives: "a more feasible alternative" or "a more effective replacement."
Exact(1)
A more practical substitute has been developed at the Massachusetts Institute of Technology, where Daniel Nocera and his colleagues have perfected cheap and durable catalysts based on cobalt and phosphate, and, more recently, on nickel and borate.
Similar(59)
There was also a more practical matter.
We need a more practical approach.
Another woman had a more practical suggestion.
And there is a more practical issue.
As a performer it is a more practical business.
Perhaps a disengagement is a more practical first step.
There is a more practical basis for the trail also.
A more practical form of folie à deux".
It had to have a more practical program.
That's a more practical and realistic approach.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com