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RSV showed a more modest effect on detection frequencies in this latter category (less than two-fold reduction).
The 9 additional non-MHC SNPs had a more modest effect on the risk of psoriasis, with each allele conferring an elevated risk of 94% or lower.
Deletion of TIF4632 had a more modest effect on the cellular transcriptome, significantly modifying the transcript levels of <1% 322 genes (19 up, 13 down) of the genome.
On the other hand, the L160K and Q161K mutations had a more modest effect, consistent with the fact that charged and polar amino acids are found at these positions in some bHLH family members [21].
Despite this increased background signal, we observed a significant growth enhancement and decrease in WGA binding when the yeast were co-transformed with Gal4AD-CAT and LOC-Gal80 (Figure 5A) or LOC-Gal11 (Figure 5B), and a more modest effect for yeast co-transformed with LOC-Rpt4 (Figure 5C) or LOC-Hap5 (Figure 5D).
Examination of transcript levels using microarray analysis (≥2-fold change) revealed a more modest effect on Salmonella transcription, with ∼11% (492 genes) and ∼8% (370 genes) of the Salmonella Typhimurium genome (4550 genes; [31]) under control of Hfq and SmpB, respectively (Table S4).
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But in a study of its own the BIS predicted a far more modest effect: less than 0.2 percentage points in most countries, though in the medium term there would be a gain from greater stability.Make me virtuous, but not yetCompelling banks to set aside a lot more capital without much warning is clearly risky.
The studies in humans demonstrated a relatively more modest effect on inflammation based on absolute numbers of macrophages, though proportional increases in inflammatory macrophages were evident.
By contrast, treatment of L-Lpcat3 KO mice with LXR agonist had a much more modest effect (45% increase).
Our results are compatible with a much more modest effect on nausea than vomiting reflected by inconsistent results in the literature.
Interestingly, a much more modest effect on HSP70 expression was observed in ALMC-2 cells, and, in contrast to the other two cell lines, a marked decrease in HSC70 expression was noted.
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