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A higher annotation ratio represents that the corresponding clustering result is better than the other ones, that is, gene are better clustered by function, indicating a more functionally consistent clustering result.
In addition, defining gene families based on features of demonstrable functionality (domains) should provide a more functionally cohesive grouping compared to assigning genes to families based on often rather arbitrary sequence similarity cut-offs.
These changes have led a more functionally rich cheminformatics library, with significant performance improvements.
With this, a more functionally complete network can be obtained.
This would provide a more functionally relevant guide to drug development strategies.
Specifically, HDX data were used to guide the homology modeling to yield a more functionally relevant structural model of DHCC.
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lie not in the formal grammars and truth-conditional semantics of the latter part of the century, but in a more functionally-oriented linguistics: that of Sapir and Whorf, Malinowski and Firth, Bühler, Mathesius and Trubetzkoy, Hjelmslev, Benveniste and Martinet, among many others (Halliday 2003b: 423).
These 'ideological antecedents', he writes: lie not in the formal grammars and truth-conditional semantics of the latter part of the century, but in a more functionally-oriented linguistics: that of Sapir and Whorf, Malinowski and Firth, Bühler, Mathesius and Trubetzkoy, Hjelmslev, Benveniste and Martinet, among many others (Halliday 2003b: 423).
In as far as there is some movement towards a more functionally-oriented approach in some T-G based studies, such as the analysis of English questions by Robert Fiengo (2007: 146, 170 1), there might now be something more of a move towards developing a consensus that both data and intuitions are needed.
Zeller evolved from a more functionally-biased CFO to the broader "executive at large" the new CEO needed.
This may allow one to better predict which members of a relatively more functionally impaired population are at greater risk for further decline or other adverse outcomes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com