The phrase "a more aggressive state" is correct and usable in written English.
It can be used to describe a condition or situation where a state or entity exhibits increased assertiveness or hostility compared to a previous state.
Example: "The recent policy changes have led to a more aggressive state in international relations, causing tensions to rise."
Alternatives: "a more confrontational stance" or "a more belligerent position."
These data suggest that PKD1 expression is decreased when cells achieve a more aggressive state.
Thus, silencing or loss of hTRM9L may be a more widespread mechanism that allows cancer cells to progress to a more aggressive state.
Stated in another way, the predictive signatures in adjacent normal tissue are a measure of the ability of the tissue to alter expression networks to enter a more aggressive state.
Cancer prevention was seen in three ways: an avoidance of risk factors, the detection of cancer at a precancerous stage and the prevention of cancer from advancing to a more aggressive state after diagnosis (Table 3).
The expression analysis of CRHBP shows that cc-RCC is characterized by a significant loss of CRHBP mRNA expression that furthermore is associated with a more aggressive state of tumors.
Although a minor inflammatory process is present in OA synovial tissue, PsA patients demonstrate a more aggressive state of synovial tissue inflammation compared with OA patients, therefore elevation in DEFA1 may be a good indicator of PsA pathogenesis.
Taken together, our findings highlight HOX gene silencing and EZH2 expression as important mechanisms to maintain UC in an undifferentiated and more aggressive state.
The Bush administration largely succeeded in a series of court fights in blocking more aggressive state regulators and prosecutors from imposing tougher standards on lenders, including those that issued what are now seen as predatory loans.
More aggressive state enforcement would almost certainly lead to cleaner government.
New Jersey has long had a reputation of being one of the more aggressive states in trying to expand health care, said Sonya Schwartz, program manager for the National Academy for State Health Policy in Washington.
A recent study in breast cancer identified an association between TEM1/endosialin expression and progressive and/or recurrent disease as well as nodal involvement, all hallmarks of a more aggressive disease state [ 6].
