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Early studies suggested a modulation of the expression of surface molecules, particularly on immunocompetent cells [ 17] which likely interferes with cell-cell communication [ 18- 20].
The implication of DAP3 in apoptosis suggests a modulation of the expression of the protein in pathological contexts such as the development of tumours.
49 Mice bearing human tumor xenografts treated with Belinostat showed a modulation of the expression of genes active in the cellular G2/M phase.
To study the mechanisms that mediate the effect of aspirin and NS-398 on anticancer drugs Caco-2 cell sensitivity, we investigated whether these treatments were associated with a modulation of the expression of these proteins.
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Modulation of the expression of TREM-1 was also affected by the type of microbial pathogen.
Modulation of the expression of carrier proteins involved in mitochondrial uncoupling was also observed.
It is unclear how NOM effects this time-dependent modulation of the expression of MDR1/P-gp.
These data were evocative of a modulation of Kit expression by Epo.
Obviously, the regulation of the expression of individual clustered miRNAs can fine-tune the pathway modulation.
Cocaine modulation of frontostriatal expression of Zif268, D2, and 5-HT2c receptors in high and low impulsive rats.
Modulation of the gene expression of SOCS3 is one suggested mechanism.
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