The phrase "a modulation of cell" is not correct in standard English.
It seems to be missing a noun to clarify what type of cell is being modulated, such as "a modulation of cell activity" or "a modulation of cell function."
Example: "The study focused on a modulation of cell behavior in response to external stimuli."
Alternatives: "a change in cell" or "an alteration of cell".
This suggests that the durability of response exceeds the circulating properties of the protein and may be via a modulation of cell phenotype.
The gene ontology analysis (Table 2) indicates a modulation of cell signalling pathways has taken place.
miR-21 directly binds to the target site in the 3′UTR of Cdc25A and suppresses its expression, resulting in a modulation of cell cycle progression following stress, without affecting apoptosis [52].
No modification in JNK and p38 phosphorylation levels was detectable by Western blot, but the ERK1/2 pathway was clearly affected, suggesting a modulation of cell survival and not a response to stress (Xia et al, 1995).
As expected, we found a modulation of both cell proliferation and differentiation in our models of osteosarcoma cells modified for MT2A compared with parental cells, and especially a strong inhibition of differentiation process without increased cell viability under MT2A silencing.
Trypanosoma cruzi is an intracellular parasite that, like some other intracellular pathogens, targets specific proteins of the host cell vesicular transport machinery, leading to a modulation of host cell processes that results in the generation of unique phagosomes.
DRO1 modulates root gravitropic response, likely via a modulation of epidermal cell elongation that enables roots to orientate their growth relative to the pull of gravity.
Flavell and coworkers showed that IL-17 has a protective function in a mouse model of inflammatory bowel disease by down-regulation of Th1 specific gene expression and a modulation of T cell mediated colon inflammation [37].
Similarly, in the presence of a BDNF (Brain-Derived Neurotrophic Factor) gradient, membrane receptors preferentially associated to lipid rafts localized on the side of the GC facing the gradient source [22], possibly causing a modulation of the cell response [23].
We also believe the perturbation has also influenced NF-kB signalling and resulted in a modulation of the cell cycle.
Furthermore, the combinatorial expression of hsa-miR-127 and EBNA1 provides evidence of a modulation of B-cell markers in human memory B cells, resulting in a decrease of BLIMP-1, XBP-1 and IRF-4, and an increase in BCL-6 and CD10 mRNA, thus confirming the scenario previously observed in EBV-positive BL primary tumors and cell lines.
