Exact(1)
The program noisy exports a Postscript file, visualizing the quality of the sites of the reordered input alignment (see Fig. 2), recording their reliability score as xy-data, and containing a modified alignment for further analysis in which sites with reliability q < q cutoff are removed.
Similar(59)
AMTP sequences generated for this study (Additional file 4) were included in a modified alignment from [ 10] and phylogenetic analysis was performed as in [ 10].
Thus, we tried a modified alignment score SL that penalizes sparsely distributed matches compared to locally enriched 'match blocks'.
The modified alignment was then used to generate a phylogenetic tree using Maximum Likelihood (Guindon et al., 2010).
All modified alignments were concatenated into a single data set for phylogeny estimation.
In order to compare block groups, the constituent blocks are first compared using a modified sequence alignment algorithm to determine similarity scores for pairs of blocks.
Based on a multiple sequence alignment, we propose a modified signature for the CDF family that takes account of newly characterised members.
In this paper, we demonstrate a modified coarse-fine alignment scheme designed for proximity lithography.
The identification of rRNA-like sequences is based on sequence alignments using a modified version of the BWA-SW program.
Thus, based on the hypothesis that function conservation is also related to sequence alignment length, we have used a modified form of Rost's equation (see Materials and Methods for details) that only selects sequences whose alignments have at least 40% identity at any alignment length.
RNAseq data were aligned to a modified version of the Genome Reference Consortium human genome build 37 (hg19, Feb. 2009) containing IUPAC ambiguous nucleotide characters for each annotated SNP in dbSNP 135 with alignment performed using SOLiD LifeScope™ Genomic Analysis Software v2.5.1 (Life Technologies Carlsbad, CA).
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