Sentence examples for a modest effect size from inspiring English sources

We analyzed multiple SNPs jointly to test whether the overall lung cancer risk was determined by the combined action of multiple SNPs within the same gene and/or of multiple genes within the same pathway, even if each SNP may have had only a modest effect size individually.

Each SNP has a modest effect size (typically 10 20% increased risk per allele).

Underpowered studies that are too small to detect a modest effect size can lead to false-negative follow-up studies.

A sample size calculation was completed with power set at 0.8, alpha at 0.05 and a modest effect size 0.7.

Therefore, even a modest effect size may be of clinical relevance to patients, although treatment-emergent adverse events need to be taken into consideration as well.

Such a modest effect size is in accordance with other emerging studies in complex disease that routinely report small changes in DNA methylation in a case control setting.

Again, after propensity score stratification, proton pump inhibitors were associated with an increased risk of pneumonia, albeit with a more modest effect size than that observed in our other analyses and with a confidence interval that intersected the null (risk ratio 1.06, 0.93 to 1.21).

A more recent replication study suggests a more modest effect size of 0.84, which would result in only 80% power to detect the association in the present study (Prokunina-Olsson et al, 2010).

When we looked at the subgroups of those with baseline A1C >7.0% at baseline, the differences in improvements in A1C increased from a very modest effect size of 0.11 for the entire randomized sample to a clinically significant effect size of 0.50.

However, only four trials (n = 326) with adequate allocation concealment, blinding and ITT analysis were located, resulting in a more modest effect size in favour of exercise.

However, due to potential difficulty of maintaining subjects in these communities in the trial, high rates of mobility, and the potential for a more modest effect size in this group, we aimed to recruit 300 subjects.