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Remarkably, aptamers blocked more than one inhibitor simultaneously, and a modest diminution of aptamer binding (3 10 fold) was only seen at the highest total inhibitor concentration (2400 nM) (Figure 1).
It is noteworthy, therefore, that there was a small but significant reduction in miR-9-2 expressinn in the Visc-2−/− brain versus controls, suggesting that the deletion of the first exon of Visc-1 has a modest diminution of transcription of the pre-mRNA9-2, which is mostly transcribed from a separate, more proximal, promoter in a neural cell line (Laneve et al. 2010).
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The modest diminution of B cells constitutes a difference with that found in adults, for instance Monserrat et al. [31] described severe abnormality of circulating B lymphocytes associated with mortality.
Western blots showed modest diminution of RPS13 at 4 hours and a marked diminution of RPS13 at 24 and 48 hours in the absence of ATc (Figures 3B and S3A).
We addressed the challenge of mitigation in the event of a modest pandemic scenario, but, in agreement with national strategic policy, we assumed no diminution of standards of care or rationing of clinical services.
Take a modest proposal.
Some earn a modest pension.
He has a modest ambition".
Here's a modest proposal.
A modest little house designed.
It had a modest impact.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com