Sentence examples for a modest activity from inspiring English sources

VLX40 had a ratio of 0.28 indicating a modest activity against solid tumors compared to cisplatin (S/H ratio 1.2).

Moreover, the combination of cetuximab plus carboplatin achieved a modest activity: 17% RR, and 31% CB [ 46].

A phase II trial of sorafenib in 37 metastatic melanoma patients reported a modest activity, with only three partial response (8% Min et al, 2008).

GAP activity assays showed that while the P1050A mutation caused a modest activity decrease, the Q1032E, N1052E and K1053A mutations largely abolished the activity.

TfuDyP shows a modest activity towards substrates that are typical substrates for plant peroxidases, such as guaiacol and 2,6-dimethoxyphenol.

Despite the well-known broad antimicrobial spectrum of defensins [ 35], crotamine shows a modest activity towards both Gram-negative and Gram-positive bacteria [ 36].

We know the mutations associated with developmental syndromes cause a modest activation of MEK activity compared with activating mutations in the activation segment.

Remarkably, only two of the three PD-linked variants of α-synuclein were IL-1β inducers in primary glia, and contrary to expectations from previous studies performed using cell line cultures and other studies involving modified α-synuclein species, our results show that the A53T α-Syn variant has instead a very modest activity in regulating the innate immune response by primary glia and microglia.

However, ATP concentrations above 0,6 mM caused a sharp decrease of the native enzyme activity and only a modest PFK1 activity was detected at ATP concentration of 1 mM (Fig. 5A).

A delay in approval of an agent with even modest activity can cause substantial loss of potential years of life [ 4].

Mutations near both these pockets also confer resistance to omeprazole, a covalent inhibitor with modest activity [30].