Specifically, in moderately adjusted models each 10-unit increase in BMI was associated with a 17% increased risk of nonaccidental mortality (95% CI: 1.09, 1.26), whereas a 10-unit increase in pack-years of smoking was associated with a 12% increased risk of nonaccidental mortality (95% CI: 1.01, 1.14).
Moderately adjusted models included additional terms for continuous measures of both body mass index (BMI; kilograms per meter squared) and pack-years of smoking.
Among men with BMI <28 kg/m (n = 1,851; 48 cases of diabetes), compared with low-active men, those reporting moderate, moderately vigorous, or vigorous activity had an adjusted (model 4) HR for diabetes of 1.12 (95% CI 0.62 1.99).
A mutually adjusted model suggested that rs3769823 explained the signal in this region.
Finally, Model 4 is a fully adjusted model (Model 4).
A fully adjusted model was computed.
Compared with infants with normal birth weight for GA, infants who were assessed as very small for GA (very SGA; <3rd percentile) had a doubled infant mortality risk and moderately small for GA infants (moderately SGA; between the 3rd and the 10th percentiles) had a 50% increased risk in the fully adjusted model (table 1).
Compared with infants with normal birth weight for GA, very SGA infants had an almost doubled risk and moderately SGA infants a 40% increased risk of postneonatal mortality in the fully adjusted model (table 3).
Older age (odds ratio [OR] per 10 years 1.42 [95% CI 1.08 1.86]) and lower comorbidity (1.60 [1.00–2.57]) were moderately associated with intensification of diabetes medications in the partially adjusted model.
Compared with normal birth weight infants, very SGA infants had a 2.5-fold increased risk and moderately SGA infants a more than 50% increased risk of neonatal mortality in the fully adjusted model (table 2).
HRs describing the relationships between ambient PM2.5 and nonaccidental and cardiovascular mortality are shown in Table 2. Ambient PM2.5 concentrations were not associated with an increased risk of nonaccidental mortality for the cohort as a whole; however, significant inverse relationships were observed among nonmoving women in moderately and fully adjusted models.
