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This indicated that a moderate down regulation of the gene expression inhibited the growth.
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In our study we readily detected the fsrB and gelE transcripts by QPCR, but growth in blood caused a moderate down-regulation of these genes in V583.
The mRNA levels of PPARγ displayed a moderate down-regulation in ANGPTL3-silenced cells upon insulin stimulation.
Cluster 4 was the most abundant group with 1,000 differentially expressed genes that exhibited a moderate down-regulation (fold-change 0.5-0.7 0.5-0.7ponse to infection.
Since in vivo we found a decrease in PABPN1 expression with age in both normal aging and in OPMD, we studied whether at with a moderate down-regulation of PABPN1 myogenic defects can also be observed.
We found anterior placental site to be significantly associated with a moderate down-towards-birth pattern (FPC2) and with a U-shaped pattern (FPC3), combining the gradual decrease in counting time with a small increase in late gestation.
In contrast, the other two sets of variants of the D.24 condition, heat-shock and starvation, show less differences: in the former 587 up-regulated genes total in the latter case of starvation 3,123 genes; however, most of them showing a moderate down-regulation of ∼log-fold change −2.
An 8-bp complementarity to the 5′ seed region (canonical 8mer site) [ 35] of the amiRPPO3 in a StuPPO4 gene sequence region might be related to an unanticipated moderate down-regulation of the non-targeted StuPPO4 gene in Line amiRPPO3-15.
For some, the essence of Huntsman's claim to being a moderate comes down to social issues – namely his endorsement of gay civil unions.
Second, microarray experiments reveal that overexpression of miRNA in cells cause the moderate down-regulation of a large number of transcripts, many of which contain the complementary sequences of the over-expressed miRNA in their 3'-UTRs [23] [25].
Moderate down-regulation of these five TFs by miR-K12-11 miR-K12-11 miR-K12-11eashouldpresultn of thein decreasedm gexpression
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