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Analysis of MsbA conformational dynamics reported previously (Dong et al., 2005; Borbat et al., 2007; Zou and Mchaourab, 2009) and extended here is entirely consistent with a model of turnover that invokes engaged and disengaged NBD states, symmetric NBS conformations, and tight structural coupling between the NBDs and the TMDs.
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A model of protein turnover and the role of the molecular chaperone Hsp90 in maintaining protein homeostasis has previously been developed [ 30].
Katz [ 38] developed a model of employee turnover whereby he identified that workers perceptions of the work environment varied according to their tenure.
These studies sustain a model of homeostatic turnover in which equally potent stem cells undergo a continuous process of stochastic loss and replacement so that their overall population is maintained.
Collectively, we favor a model of enhanced Treg turnover in the target organ during active MS, which might influence the homeostatic composition of the Treg pool.
We conclude that the diminution of H2BGFP intensity in the adipocyte population is consistent with a model of rapid adipocyte turnover.
By examining the conservation of binding sites identified in Saccharomyces cerevisiae, we found that while some transcription factor's binding sites are consistent with a model of binding site turnover, a quarter of the transcription factors are consistent with some amount of regulatory divergence.
In sum, we propose a moderated mediation model of turnover intention: Employees' psychological ownership is related to turnover intention (partially) via conducting territorial behavior.
Degradation of c-FLIP by ubiquitinylation was investigated in a mathematical model of the dynamic turnover and stability of c-FLIP isoforms by Toivonen et al. Bagci et al. created a model of the bistabilty switch between apoptosis and survival based on the regulation of nitric oxide species and inhibition of caspase-8 and -3 by nitric oxide species.
Here, we propose an alternative approach based on a stochastic model of TFBS turnover.
In their study, Hendershott and his colleagues created a statistical model of housing turnover from 2005 through 2011 in Illinois Cook Countyy.
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