The cirrhogenic ability of thioacetamide has been used to induce a model of chronic generalized liver disease that resembles the preneoplastic state of human fibrosis.
This finding is consistent with the metacognitive model of generalized anxiety disorder (Wells, 1995), in which positive metacognitive beliefs guide the selection of worry as an effective coping strategy, which, in turn, increases emotional distress.
Generally, the ability of a model to generalize to new populations and nominally unrelated individuals will depend on the trait architecture; for a finite, relatively small, number of training samples, the larger and fewer the genetic effects associated with a trait the easier it will be for a model to separate this predictive signal from other data structure.
Recent models of generalized anxiety disorder (GAD) have expanded on Borkovec's avoidance theory by delineating emotion regulation deficits associated with the excessive worry characteristic of this disorder (see Behar, DiMarco, Hekler, Mohlman, & Staples, 2009).
At the same time, the method proposed should facilitate the study of electrode reactions with two charge-transfer steps under both charge-transfer and linear-diffusion control and that of a model involving generalized higher-order charge-transfer processes coupled with semi-infinite linear diffusion.
The framework can be generalized to a model of endogenous choice of informality.
A model of particular interest is the Generalized Statistical Thermodynamic Adsorption (GSTA) isotherm.
For example, Pinker & Prince (1988) point out that the model does a poor job of generalizing to some novel regular verbs.
This hierarchy, founded on a pharmacological model of therapy, is generalized to other interventions which may be complex and non-pharmacological (healing, acupuncture and surgery).
