The phrase "a model of disruption" is correct and usable in written English.
It can be used to describe something that exemplifies or represents a significant change or upheaval in a particular field or context.
Example: "The startup has become a model of disruption in the traditional retail industry, challenging established norms and practices."
Alternatives: "an example of upheaval" or "a paradigm of change".
In fact, in the fathead minnow, a species that serves as a model of vertebrate endocrine disruption, vinclozolin exposure resulted in a slight increase in estradiol concentrations in adult male fish [ 13].
For example, spinal nerve ligation in a model of neuropathic pain led to disruption of autophagy flux in the dorsal horn (8, 77).
These classes agree well with a model of chromatin in which local disruptions (DHSs) are concentrated within larger domains of intermediate sensitivity, the accessibility islands.
If you apply this model of disruption to past fads, you can predict with incredible reliability which products turn into long-term successful businesses and which ones don't.
Finally, our finding that transitions to hypersensitive states are very uncommon from the insensitive state supports a model of chromatin in which local hypersensitive disruptions are concentrated within larger domains of intermediate sensitivity, forming accessibility islands.
The experimental model, social disruption (SDR), is a model of social stress in which mice are repeatedly attacked and defeated in their home cage by an aggressive conspecific.
Since aminoguanidine can also inhibit the formation of advanced glycation endproducts [28] we next used a genetic model of iNOS disruption to further demonstrate the role of iNOS in LPS-induced IR.
Furthermore, a rodent model of Avp disruption displays schizophrenic endophenotypes [ 36], and levels of both AVP and NTS have been reported to be altered in schizophrenia [ 37, 38].
In the present study, we have tested this hypothesis by analysing a murine model of targeted disruption of the ISC synthesis-modulating frataxin gene in mammalian liver, as well as two model systems overexpressing frataxin, with respect to DNA repair and tumour initiation.
Models of disruption to the TH pathway have strikingly similar pancreatic phenotypes to IGF pathway mutants, suggesting that they are secondary to IGF pathway disruption.
