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Here, we use CD4+ T cells as a model of differentiation, mapping the activity of cell-type-specific enhancer elements in T helper 1 (Th1) and Th2 cells.
Recent data suggest a model of differentiation from naïve to antigen-specific memory T cells based on the lineage markers CCR7, which is a lymph node homing receptor and the RA isoform of CD45, which is a marker expressed on naïve lymphocytes, and is re-expressed at the fully mature stage of differentiation.
PC12 cells have been extensively used as a model of differentiation.
Rogers et al., used a model of differentiation that is dependent on the initial dose and affinity of peptide presented to a naïve CD4 cell.
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We estimate demand for automobiles in Greece using a model of product differentiation and use the model to evaluate carbon-based tax schemes that could shift consumer purchases towards low CO2 emission cars.
F3.Olig2 cells express oligodendrocyte markers and represent a model of NSC differentiation (Fig. 1).
We have used BeWo cells as a model of trophoblast differentiation and fusion.
To assess potential miR-132 targets, we used a whole-genome microarray in PC12 cells, which have been used as a model of neuronal differentiation.
The findings of our study suggest a model of adipogenic differentiation involving two modes of epigenetic mechanisms.
Pheochromocytoma (PC12) cells, originated from a rat adrenal medullary tumour (pheochromocytoma) have been widely employed as a model of neuronal differentiation and neurite outgrowth [ 21].
We propose a model of geographic differentiation followed by human-associated admixture, primarily between European and Asian populations and more recently between European and North American populations.
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