Sentence examples for a model of depression from inspiring English sources
The phrase "a model of depression" is correct and usable in written English
It can be used to describe someone or something that exemplifies the characteristics or symptoms of depression, often in a figurative sense. Example: "Her behavior during the past few months has become a model of depression, showcasing the signs of withdrawal and sadness."
Stereotaxic pharmacological (Winter et al, 2011) and stereotaxic electric (Li et al, 2011) inhibition of the LHb have been found to lead to the improvement of depressive-like behaviour in translation studies using a model of depression with the Learned Helplessness paradigm.
In fact, housing in isolation affects the cognitive function of an animal and is even used as a model of depression in research [14, 15].
In the experimental animals, chronic stress paradigms are considered as a model of depression, and in that context are used for examining the effects of different drug treatments.
These findings suggest a model of depression in which a circuit including the PFC, amygdala and hippocampus influences not only mood regulation, but also learning and contextual memory processes [ 88].
For example, Surget et al. [ 45] showed specific transcriptome changes in different brain regions using the unpredictable chronic mild stress paradigm, a model of depression based on socioenvironmental stressors.
These changes could reflect the strong genetic divergence between WKY and BN strains [ 37] as well as signatures of physiological features that characterise these strains; for example, the WKY strain shows resistance to mammary cancers, exhibits exaggerated neuroendocrine and behavioural responses to stress and is used as a model of depression [ 38, 39].
Similar behavioural results were obtained in the chronic stress depression model with CD1 mice [ 42] and in a model of elderly depression in 18-month-old C57Bl6N mice [ 41].
For example, it is known that a model of synaptic depression can destabilize a spot in favor of a traveling pulse [25].
Indirect confirmation comes from the profile of Ind mice (considered a model of mild depression [34], [69] [72]) which showed lower feeding and body weight gain in the absence of any sympathetic hyperactivation when fed chow diet while becoming hyperphagic and obese in the presence of HFD.
Integrating these lines of evidence, we propose a model of comorbid depression with AUD.
As another example, Bowens et al. [ 56] developed a model of atypical depression in the rat that largely relied on hyporesponsiveness of the HPA axis, resembling a distinctive feature observed in this subset of patients.
