The phrase "a model of defect" is correct and usable in written English.
It can be used in contexts where you are describing something that exemplifies a flaw or imperfection, often in a technical or analytical discussion.
Example: "The prototype was a model of defect, showcasing all the issues that needed to be addressed before the final version could be released."
Alternatives: "an example of failure" or "a representation of flaw."
We therefore studied the restoration of articular cartilage by blocking VEGF signaling with bevacizumab in a model of osteochondral defects in Japanese white rabbits.
Consistent with a model of neuronal migration defect as the cause of molecular layer heterotopia (MLH), Bergmann glia in heterotopia exhibit morphological abnormalities with radial fibers that fail to reach the pial surface [ 11] or with fibers that inappropriately cross into the adjacent molecular layer [ 13].
Our data support a model of early carcinogenesis wherein defects in the process of inactivation of lung stem-cell associated genes during differentiation, contributes to the development of carcinogenesis.
Tommiska et al (2008) have recently proposed a model of 'conditional haploinsufficiency', whereby defects in genes such as BRCA1 or BRCA2 can disrupt the regulation of other important genome integrity monitoring genes such as ATM.
To reduce these defects, a model of centrifugal casting WTCL based on the ProCAST software was constructed in this study, and the simulated result was used to optimize the casting process.
The TD gene cluster is considered a model of hereditary diseases resulting from defects in several of its homologous enzymes in humans (Peñalva 2001).
Furthermore we analyse their functionality in vitro, and in vivo after transplantation of iPS-RPE into the dystrophic RCS rat: a model of retinal dystrophy where the primary defect, originating in RPE cells [26], leads to blindness as a consequence of rod and cone photoreceptor degeneration[27] [29].
Optimizing the system facilitated the identification of a contraction force defect in a model of hypertrophic cardiomyopathy (HCM), a disease affecting ∼1 500 of the population.
In a rat sciatic nerve model, Lin and coworkers created a 5-mm nerve defect as a model of nerve coaptation under tension and repaired the nerve with 10-0 nylon epineural sutures, fibrin glue, or PEG hydrogel [ 69].
This was likely due to a direct impact of ICOS deficiency on Foxp3+ Treg cells, as ICOS−/− Foxp3+ Treg cells show intrinsic functional defects in a model of Type 1 diabetes 19.
