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Mike Lynch, Autonomy's CEO, points out that the IDOL platform does not rely on a model of content that must be maintained.
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We find that CpG hypermutability in chicken acts to keep the GC content at its current mean, whereas GC content would be increasing under a model of GC content evolution that neglects CpG hypermutability.
In human, CpG hypermutability leads to a decrease in GC content over time, whereas GC content would be kept at its current mean under a model of GC content evolution that neglects CpG hypermutability.
The accuracy and precision of each method was assessed numerically by fitting a model of DNA content change through the cell cycle to the histograms of nuclear DNA content and flow cytometry data, the results of which are shown in Table 1.
Inclusion of these methylation maps into a model of GC content evolution provided significant support for the impact of DNA methylation on the local equilibrium GC content.
We incorporated data from these maps with estimates on recombination rate into a model of GC content evolution in order to investigate the impact of DNA methylation on the local equilibrium GC content (GC*).
She likens the system to a model of the content world on Canopy's servers.
To investigate the impact of DNA methylation in more detail, we incorporated DNA methylation into a model of GC content evolution.
In the following, I will therefore consider equations (21) and (22) as giving the best testable approximations of and corresponding to a model of GC content evolution driven by replication errors.
In summary, a model of GC content evolution driven by gBGC linked to mitotic recombination, either associated with parasexuality or with damage repair, can account for the strong anticorrelation between and observed in C. albicans and C. dubliniensis.
The Hopfield neural network is a model of associative content-addressable memory with a simple flexible structure.
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CEO of Professional Science Editing for Scientists @ prosciediting.com