GIPR dn transgenic pigs resemble characteristic features of human type 2 diabetic patients with impaired insulinotropic action of GIP, reduced glucose tolerance and insulin secretion as well as a reduction of β-cell mass, and are therefore a relevant model for numerous applications in basic as well as in translational research.
She was a pioneer before the word "feminist" existed, achieving her positions on merit and served as a role model for numerous generations of attorneys.
Our motivation for considering diffusion fields is based on the fact that diffusion fields provide a suitable model for numerous natural phenomena in biology, physics and engineering: from the release of pollutants [8], to the modeling of biochemical leakages and nuclear wastes[9].
It is well known that the theory of impulsive differential equations has been recognized to not only be richer than that of differential equations without impulses, but also to provide a more adequate mathematical model for numerous processes and phenomena studied in physics, biology, engineering, etc.
After the blood in your veins has thawed and you can once again feel a pulse, think about the famous "Pyramid of Philanthropy" which has served as a model for the efforts of numerous performing arts organizations as they try to expand their audiences.
This bacterial enzyme has been the model for numerous studies aimed at deciphering the catalytic mechanism of oxalate decarboxylase.
In this study, we have performed the first large-scale EST sequencing project using a model for fracture healing and have identified numerous differentially regulated genes not previously known to be involved in fracture healing.
It might serve as a role model for the numerous divorcees who reckon that "having been bitten once, I won't risk it again", and so live with their new partners without marrying or exchanging vows.
However, we would like to note that mimicking slow, adult-onset degeneration as it occurs in patients over many years is a problem in all animal models, including mouse models for numerous neurodegenerative diseases.
