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We found core sets containing between six and 34 TFs, depending on the virus, whose in silico knockout or overexpression in the TRN resulted in transcriptional profiles that minimally deviate from those observed in infected plants.
Our approach compares the transcriptomic profiles of non-infected plants with those observed for virus-infected plants and searches in silico for those minimal sets of TFs or genes whose alteration (knockout or overexpression) results in a predicted transcriptomic pattern that minimally deviates from the observed in infected plants.
This end-point is reasonable and acceptable in this setting at this time, since, for the most part, the Kaplan-Meier probability of surviving declines exponentially and survival in patients treated with current agents minimally deviates from this expectation.
ATMOSPHERE Neapolitan home cooking in a minimally adorned dining room.
At first in a coma, he was left in a minimally conscious state (MCS), or minimally and inconsistently aware.
Should Boeing launch a minimally viable airplane?
Earth Day began as a minimally organized teach-in.
One approach is to suggest a minimally invasive compromise.
He said Ms. Lilly was in a "minimally conscious state" rather than a persistent vegetative state.
Rudin described the star as "a minimally talented spoiled brat" in possession of a "rampaging ego".
Should GE Healthcare launch a minimally viable CT scanner?
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com