Prior to running the back-translation algorithm, users are asked by Gene Composer to select a codon usage table (CUT), define a minimal codon usage frequency threshold to eliminate the use of "rare" codons and set a target guanine:cytosine percentage (G C%) content for the intended expression system.
Boyle tells us that the new app, which replaces a stagnant 16-month old version with "minimal" usage, is meant to be a facelift for the Global Grind brand itself.
"You almost want to know what the minimal usage is — once a month?
Supercritical fluid extraction involved a short extraction time and the minimal usage of small amounts of entrainer in the CO2.
However, when ART is administered based on the hybrid BFPSO algorithm, the CD4 cell count increased to a value of 782 cells/mm, with minimal usage of the drug concentration.
For example, enzymes for metabolic subsystems which are frequently used, such as glycolysis, tend to be maintained at high stable levels, compatible with a high usage of static resources, but minimal usage of dynamic ones.
We thus expect that RA FLSs could be reprogrammed into iPSCs using minimized conditions, which would facilitate the minimal usage of oncogenes such as c-myc and klf4.
I would be much more interested if authors 'formalism could quantify what they stated in the discussion section: "… enzymes for metabolic subsystems which are frequently used, such as glycolysis, tend to be maintained at high stable levels, compatible with a high usage of static resources, but minimal usage of dynamic ones.
Although a larger percentage of patients receiving non-taxane-based chemotherapy would have allowed for a more accurate analysis on the effects of taxane, the minimal usage of anthracyclines alone in our cohort reflects standard practice and guidelines for systemic treatment.
