Interestingly, another obligate intracellular pathogen, Coxiella burnetii, that occupies a phagolysosomal-like vacuole [55], also exhibits a minimal capacity to respond to iron availability [17].
The screening of ~800 miRNA transcripts using NanoString profiling resulted in a minimal number of responding targets.
As mentioned before, there is current clinical interest in using low dose estradiol therapy to treat antihormone resistant breast cancer [ 24] however only a minimal 30% of patients respond to this therapeutic strategy.
11 In a recent survey, 1018 neonatologists from 11 countries responded with a minimal variability, that in the first week of life higher haematocrit thresholds were targeted irrespective of the degree of respiratory support.
We were able to document that the surviving β-cells not only contribute a minimal amount of insulin but respond to various stimuli with prompt insulin release.
By contrast, pZ310 which is expressed from a minimal heat shock promoter responds to the tissue-specific control that restricts its expression to the posterior follicle cells, but is insensitive to the line-specific control, since it is expressed in both the U and S genetic backgrounds (Fig. 1).
Aug. 16: Intelligence intercepts suggest that North Korea will respond to even a minimal U.S. military strike by launching conventional missiles at Japan, and to a broader strike by turning Seoul into "a sea of fire".
We propose that their relatively constant environmental niche has led to a minimal requirement for R. rickettsii to respond to environmental changes with a consequent deletion of non-essential transcriptional response regulators.
However, the call-handler interprets the response by stating 'so I would say Asian'(line 6) to which the caller responds with a minimal confirmation 'Mm' (line 7).
The opposite strategy is to maintain a minimal enzyme level, but be able to respond quickly.
