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As shown the representative recordings in Figure 7A1 and I V curves in Figure 7A2, 0.5 mM [Ca]o depolarized the membrane potential in the control groups, but with a minimal effect in U-type dsRNA/siRNA treated groups.
Compared to the robust granzyme B induction with anti-4-1BB on reactivated memory cells, anti-4-1BB was found to have a minimal effect in enhancing granzyme B expression on primary effectors derived from naïve CD8 OT-I (Fig. 4F).
He found no effect on the GPs' performance and a minimal effect in terms of the patients' cardiovascular risk reduction.
AG however had only a marginal effect in reducing aortic O2- production, which corresponded to a minimal effect in improving aortic nitric oxide (NO) bioavailability.
Since long-term eRapa treatment may at least partially mimic chronic DR in lifespan extension, we predicted that it would have a minimal effect in Rb1 +/− mice.
However, we saw no evidence for significant modulation of UP states by application of dopaminergic antagonists alone, suggesting that the off-target activation of 5HT1C and 5HT2C receptors had a minimal effect in our model.
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In contrast, a minimal effect was observed in normal or tumour cells expressing low levels of active Akt (Jetzt et al, 2003).
The results show that load cycling, beyond the first cycle, has a minimal effect on TCC, in disagreement with other studies in the literature.
Treatment with anti-retroviral drugs has decreased mortality from AIDS in industrialized countries but has had a minimal effect so far in developing countries [ 14].
No suppression of these already low levels of cell cycle proteins in response to si CXCR7 was observed in wt-MCF7 cells in the absence of E2, and only a minimal effect was evident in the presence of E2.
These results are consistent with our previous findings, demonstrating induction of apoptosis by F but only a minimal effect on proliferation in both BT474 LR and LTR cells.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com