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The phrase "a milestone in one" is not correct and lacks clarity in written English.
It could be used in a context where you are referring to a significant achievement or event that impacts an individual, but it needs more context to be meaningful.
Example: "Completing the marathon was a milestone in one’s personal journey towards fitness."
Alternatives: "a significant achievement for one" or "a landmark moment for one".
Exact(2)
"I also think that coming back from two sets and a break is also sort of a milestone in one's career.
If I drove with you down the stretch of Flatbush Avenue from Kings Plaza to the Brooklyn Bridge, I could probably tell you a story about a milestone in one of my grandparents' or great-grandparents' lives by passing certain landmark buildings (thanks, Dad).
Similar(58)
That will not solve all the school's problems, but it would be a remarkable milestone in one village's struggle to provide good education for its children.
The recent sequencing of the entire genetic code of Arabidopsis, a common laboratory plant, is clearly a milestone in genetic engineering, one that will reduce the cost and increase the speed of commercial applications.
"A milestone in a young ones life.
'Live,' No Regis, No Kelly It was a milestone in television, though perhaps not one to brag about.
It hopes that last week marked a milestone in the plight of the one in five of the working population who day in, day out, fail to make ends meet.
She said, "Each one marks a milestone in my own political history".
Without quite the drama of Alexander Graham Bell calling out, "Mr. Watson, come here!" or the charm of the original "Star Trek" television show, scientists have nonetheless achieved a milestone in communication: teleporting the quantum identity of one atom to another a few feet away.
This not only marks a milestone in the career of the artist, but one in the short history of dance music at the iconic arena as well.
One of a dozen Kurosawa masterpieces, Rashomon is a milestone in cinematic and cultural history.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com