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If this study can stand the test of time, it will be a milestone discovery in biology.
In doing so, he discovered an important role for p53 in apoptosis – a milestone discovery that opened up new avenues of research into the origin of cancer.
For instance, the identification of the Drosophila Toll receptor was a milestone discovery, since later it was found that related PRRs of vertebrates, the so-called Toll-like receptors, also play a dominant role in the innate immune system of vertebrates [ 8].
A milestone discovery is that instead of merely being a contributor to energy excess, overnutrition has been recognized as an independent environmental factor that is targeted by innate immune system to trigger an atypical form of inflammation, which leads to metabolic dysfunctions at cellular, organ, and systemic levels [ 20- 33].
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Dyer asked the clinicians if the 1986 discovery of the gene responsible for retinoblastoma--a milestone discovery in basic research, as it was the first human-disease gene to be cloned--had made a difference in the lives of the patients.
The milestone discovery was presented Wednesday at a conference of the American Astronomical Society in Texas and also published in papers in Nature and the Astrophysical Journal Letters.
Sixty years ago, the milestone discovery of the double-helix structure of the DNA molecule opened a door for scientists to uncover the secret of life.
Although the neuropathology of HCHWA-D is clearly distinct from that of AD, this milestone discovery provided the first evidence that the APP gene harbors autosomal-dominant mutations causing dementia.
Stefan Jentsch, a molecular cell biologist, made numerous milestone discoveries studying the function of ubiquitin and ubiquitin-like proteins.
Although there has been a dramatic increase of research into the epigenetics of breast cancer and milestone discoveries have undoubtedly been made, the application of such findings into the clinical setting has been slow.
They enabled milestone discoveries in pharmacology and biochemistry ranging from the original formulation of the receptor concept, the first isolation and structural analysis of a receptor protein (the nAChR) to the identification, localization, and differentiation of its diverse subtypes and their validation as a target for therapeutic intervention.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com