In addition, larvae with a weaker Cdipt mutant allele, cdipt lop (lop) (Murphy et al., 2011), which carries a point mutation in the phosphatidylinositol synthase (PIS) domain, also replicated the hi559 GI phenotype (supplementary material Fig. S1C), but exhibited a milder, delayed phenotype.
"What can we do?" Still, a savvy cyclist should be able to complete his deliveries safely and legally with only a mild delay, said Kevin Bolger, 40, a longtime bicycle messenger known as Squid.
The defects in looping ranged from a mild delay to a completely unbent tube (Fig. 5D).
This observation suggests that the mutation may cause a mild delay in G1, consistent with the increased doubling time and profile of DNA replication observed for elm1T551A.
At a pre-school age, she showed a mild delay in developmental milestones.
Our data show that transcripts involved in this pathway are also dynamically regulated, and they follow the general trend of photosynthetic electron-transport reactions with a mild delay.
Compared with OLIG2, OLIG1 plays a secondary and nonessential role in oligodendrogenesis as OLIG1 null mice lines have shown only a mild delay in oligodendrocyte differentiation and maturation without long-term effect [ 137].
Importantly, teriflunomide treatment in this viral model of MS only resulted in a mild delay in the production of antiviral antibodies and was associated with a transient, non-significant increase in viral load in the CNS 30 days post-infection.
When cells are released at 32°, the entry into S phase was advanced in both ERG26 and erg26 cells, but the erg26 cells still exhibited a mild delay in S-phase progression compared with the ERG26 control.
We have shown a mild delayed-onset liver injury in C57BL/6 mice that may be the basis for an animal model if a method can be found to increase liver injury.
