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All nerve specimens revealed a mild (up to 25%) to marked (25 50%) reduction in myelinated nerve fibre density associated with variable endoneurial fibrosis and subperineurial oedema (Figure 1C).
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In both epithelial cell lines (AGS and MKN74), a mild up-regulation (∼2-fold) of miR-26a was observed.
A mild up-sloping of the VO2 plateau (slope <10%) should not be confused with oxygen dependency.
Our methodology in which we measured gene expression in total adipose tissue might possibly not be sensitive enough to measure a mild up-regulation of IL4 or IL13 only in adipocytes.
The over-expression of COX-2 mRNA in SCDH was only detected at 6 h after CFA treatment (P < 0.01), and a mild up-regulation of COX-2 mRNA in SCDH was detected at 25 and 49 h after CFA injection (P > 0.05).
We also checked the expression of bcl-2 family proteins, regulators of drug-induced apoptosis, and found a mild up-regulation in cl-1 and remarkable up-regulation in cl-2 and cl-3 in Bcl-2 protein expression without a significant alteration in other bcl-2 family protein expressions.
Interestingly, when we examine Sox9 transcriptional regulation in the absence of cycloheximide, we see an initial mild up-regulation of Sox9 gene expression at 2 hours, but then see a sustained inhibition of Sox9 expression at 4 and 8 hours.
Look for pricing to take a mild step up from the Murano's current $29,000 base figure when the car arrives in US showrooms in late 2014.
Not a mild, 'set up a Spotify playlist consisting of nothing but different versions of "Adam's Song"' depression, but the full-blown, 'turning your arms into crazy paving with a Stanley knife' depression.
In the L5 and S1 area, if epidural fat occupied a cross-sectional area up to that of the dural sac, it was considered mild; up to twice was moderate; and greater than twice was severe.
The induction of TNFα at the mRNA level was only mild (up to two-fold).
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