Despite previous observations indicating that the Nra regulator is under the control of MsmR [23], we detected only a mild difference (1.6 fold in 2 out of 3 experiments) in the amount of nra transcripts at the two investigated pH conditions.
"That is a pretty mild difference in a point score.
Despite the mild difference in the activated protein kinases, it is likely that this promoting effect induced by E2-BSA and BPA is mediated via the same GPCR membrane receptor, an ncmER.
In addition, 203 new pathways showed a significant Z score after CR, but with overwhelmingly mild differences in expression.
This lack of hyperinsulinemia is probably due to the young age and genetic background, because female PKBβ KO mice on a genetic background displaying a more severe IR phenotype have a weaker IR phenotype than male mice and only mild differences in circulating insulin levels up to 24 weeks of age (Garofalo et al., 2003).
In conclusion, our developmental study provided evidence that there are mild differences in the quality of sensory integration relative to postural control in children and adolescents.
This developmental study provided evidence that there are mild differences in the quality of sensory integration relative to postural control in children and adolescents.
In kidneys, mild multifocal tubular abnormalities were observed in subsets of both nanoparticle injected and non-injected groups, leading to the conclusion that these mild differences in histological appearance were not related to nanoparticle injection.
20 That study utilised serum creatinine levels rather than an estimate of glomerular filtration rate to assess renal function and compared the impact of relatively mild differences in renal function (serum creatinine concentrations <80, 80-94, and ≥95 µmol/L).
Similarly, there was a mild but significant difference in the brain temperature profile [ F(18, 297) = 5.89, P < 0.0001, Fig. 6D].
