The phrase "a mild accumulation of" is correct and usable in written English.
It can be used to describe a gradual or slight increase in something, often in a context where the accumulation is not overwhelming or severe.
Example: "After weeks of rain, there was a mild accumulation of water in the basement, but it was manageable."
Alternatives: "a slight buildup of" or "a gentle increase in".
"I grew up in a new town, Hemel Hempstead, where there was absolutely no vowel meadow, and where the spoken language was flat, a version of London watered down by a mild accumulation of the various modes of speech of the many people who had moved there from all over the place".
EM analysis of Pik3c3 null embryos revealed a mild accumulation of enlarged vesicles inside lipid droplets in mutant visceral endoderm cells.
Moreover, with single Bicalutamide or trehalose treatment, autophagy blockage by 3-MA results in a mild accumulation of mutant AR species, but not statistically relevant.
On endoscopy there were multiple petechial hemorrhages generally distributed on the laryngeal mucosa and a mild accumulation of mucus in the trachea.
In general, we noticed that proteasome inhibition caused only a mild accumulation of some VAPB-interacting partners, with ratios mostly below twofold.
Two well-known inhibitors of VCP, Eeyarestatin I (EerI) and ML240 led to a mild accumulation of ubiquitinated proteins, while only ML240 also caused LC3-II buildup, in line with previous findings; however, they did not induce poly ADP ribose polymerase (PARP) cleavage or Hsp70.
In addition, although we revealed a milder accumulation of wild-type as well as mutant SOD1 onto ALS2/LC3-double positive autophagosome-endosomal compartments in motor neuron-like cells under dysfunctional lysosomal conditions, ALS2 per se seems to play a limited role in the SOD1 degradation in cultured cells (data not shown).
Knocking down of pkc-3 did not show any obvious effect on the fluorescence signals for GFP-SNB-1 and GFP-SNAP-29, whereas for GFP-SYX-4 a mild accumulation was observed in the intestine of wild-type animals.
In a single patient, mild accumulation of 100-200 nm granules was found.
In contrast to medium-chain acylcarnitines, mild accumulation of long-chain acylcarnitines is observed in healthy children due to activated mitochondrial fatty acid oxidation during catabolism [5].
In our experiments, we frequently detected mild accumulation of the full length N protein in Nnd1-dse embryos for a brief period (between 15 to 30 minutes) after transfer to the restrictive temperature and before the accumulation of Nintra (data not shown).
