Similarly, histopathological examination of the retina from tert+/+ and tert+/− zebrafish did not reveal any microscopic alterations (Fig. 2C), whereas retina from tert−/− zebrafish showed a clear atrophy of the layer of rod and cones, which had a disorganized appearance, and a reduction in the thickness of the pigment epithelium, suggesting retinal cell degeneration (Fig. 2C).
What if we could, with the push of a button, make microscopic alterations of a few neurons, causing the happy chemicals to ring out in a jackpot celebration, with no side effects?
Some animals were killed 12 h later to evaluate NOS activity and iNOS expression, as well as microscopic alteration of placenta tissues.
Besides, no macro- or microscopic alteration was detected in the liver, kidney, or stomach.
Every time I play a song, there are microscopic alterations in how I phrase this or that word, or play a chord.
All microscopic alterations were found at a very low frequency.
Fisher's exact test was used in the association analysis, whereas Student's t-test was used to compare the means of the grades of the macroscopic and microscopic alterations, since there was a normal distribution of data.
The microscopic alterations of psoriatic plaques include an infiltration of immune cells in the dermis and epidermis, a dilatation and an increase in the number of blood vessels in the upper dermis, and a massively thickened epidermis with atypical keratinocyte differentiation.
These effects elicited by PB and PTU in this short-term study, specifically, increases in TSH levels resulting in microscopic alterations of the thyroid gland, are suggestive of a potential thyroid tumor response after longer-term exposures in male rats (Capen 1997).
However, Morcher et al. were not able to find an association between ABCC6 variants and sCAD patients with pronounced electron microscopic alterations in the dermal connective tissues [ 140].
