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To reveal the topological arrangements of various E. coli replisome complexes, we developed and applied a computational method, an overview of which is depicted as a flow diagram (Figure 2).
Fig. 4 Method overview.
Figure 2 Method overview.
Section proposes the "Method overview".
All in all, I find this paper is a mixture between an opinion piece, a methods piece, and an overview piece.
Referee Comment: " All in all, I find this paper is a mixture between an opinion piece, a methods piece, and an overview piece.
Beside different F-labeling methods, an overview of other opportunities to efficiently label RDG peptides is provided.
The latter gives an historical background of the Space-Time Budget method and an overview of what the method entails.
The Materials and Methods give a good overview of the reagents and methods used for the IHC, but there is little information about the western blotting.
While we investigate a small set of interpolation methods only there also exist other methods (for a comprehensive overview see [24]).
Consequently, 'AOA estimation methods' section provides a brief overview of AOA estimation methods and describes the MUSIC and MVDR algorithms.
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