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Their approach, copied from the great chemist Linus Pauling, then at the California Institute of Technology, was to build exact scale models of the DNA that would be compatible with the limited information available from X-ray crystallography, a method of probing a chemical's structure with X-rays.
Despite ultrasound having been demonstrated as a method of probing the internal structures of teeth more than 40 years ago, development of a clinical tool has been slow.
We provided a method of probing 3D structure in its native form over time and linking matrix dynamics with cellular organization and function using graph theory.
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Neutron radiography is a powerful method of probing the structure of materials based on attenuation of neutrons.
A common method of probing the structure of these materials is extended X-ray absorption fine structure (EXAFS).
Clinical Judgement analysis offers a quantitative method of probing the judgments of patients and to identify systematic differences in their perceptions of risk and benefit [ 8].
In these studies, subtype-specific ligands could have provided a convenient method of probing the character of receptors, but it was only recently that ligands were identified that could distinguish 5-HT3A from 5-HT3AB recepTable(Table 1).
The optical redox ratio (NADH fluorescence intensity divided by FAD fluorescence intensity) is a proven method of probing cellular metabolism and has been used to differentiate cancerous from non-cancerous tissues in a variety of models including oral and breast cancer [ 21– 27].
This basic structure tolerates numerous modifications to the peptide sequence, which are an important method of probing the mechanism of self-assembly and surveying the sequence structure relationship.
The results show that the ultra-microelectrodes offer a simple and reliable method of probing the solution composition under conditions where large area electrodes cannot be used.
A prior RE-based method of probing chromatin accessibility genome-wide (called NA-Seq) revealed that accessibility of regulatory regions of genes correlated with their gene expression patterns [ 35].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com