The phrase "a member of pathways" is correct and usable in written English.
It can be used when referring to someone who is part of a specific group, organization, or program named "Pathways."
Example: "As a member of pathways, she actively participates in community service projects and leadership training."
Alternatives: "a participant in pathways" or "an affiliate of pathways."
Let P be an N row by M column binary matrix, P∈ {0,1} N×M, where p ij (the element in the ith row and jth column of matrix P) is equal to 1 if gene i is a member of pathway j, and p ij = 0 if gene i is not a member of pathway j.
We use equation (3) to define if gene i is a member of pathway j, which is true if a ij = 1, and if that is the case to define if the gene is up-, down-regulated or stable.
We treat a pathway as a set of proteins a human protein h can be a member of several pathways depending on the biological processes it is involved in.
The difficulty is that pathways are complex and not mutually exclusive, so defining which pathway a mutation impacts can be open to interpretation; for example, KRAS is a member of 34 pathways and PIK3CA belongs in 37 [ 6].
In the simplest case of a gene that is a member of two pathways, its allocation is represented by a string of two binary digits.
Further, many biclustering algorithms allow a gene or a sample to participate in multiple biclusters, reflecting the possibility that a gene product may be a member of multiple pathways.
Importantly, interactions are curated between molecules in the pathway and all other interactors regardless of whether the interacting molecule is a member of the pathway or has any known role in innate immunity.
The important finding was that p38, a member of MAPK pathway was found to regulate the expression of miR-373 in glucose-induced cardiomyocyte hypertrophy.
The XPD gene is a member of NER pathway and encodes a protein involved in DNA transcription, whereas XRCC1 and XRCC3 are essential for base excision repair (BER) process.
