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The scaffold is founded on a mediating duplex that cohybridizes with two DNA/violet cluster conjugates.
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Furthermore, the scaffold constrains the cluster environment through the length of its mediating duplex.
SMARCAL1 possess a novel annealing activity rather than conventional strand separation helicase activity, which allows the enzyme to mediate duplex formation from RPA-bound DNA single strands (Yusufzai and Kadonaga 2008).
Base-pair-mediated duplex formation between these potentially natural oligomers and complementary RNA and DNA sequences was prevalent, but with an unexpected result: while 2,4-diaminotriazine-tagged backbones in all these series were found to be uniformly stronger base-pairing partners, the corresponding complementary dioxotriazine-tagged series exhibited (very) weak or no base pairing.
We introduce trust as a mediating variable.
However, we were previously unaware of any ordered water molecules mediating polymerase−DNA duplex interactions (6).
All these results suggest that the five conserved water molecules mediating polymerase−DNA duplex interactions among B family polymerases are indeed important for primer extension because they are specifically involved in recognition of W−C base pairing geometry of DNA duplexes.
Docking of D3 is mediated by a short duplex that is found at the base of D2.
Recently we showed that Mtb DnaA in-vitro can mediate DNA duplex unwinding in the vicinity of this sequence [36].
"It can transform a studio into almost a duplex apartment.
It was quite a nice apartment, actually a duplex.
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