In a recent example, a mechanistic model was applied to predict systemic exposure following inhaled administration of SGRM in healthy volunteers using six different devices and formulation.
As an example, we used a mechanistic ecohydrological model, T&C (Fatichi et al. 2012, 2015; Fatichi and Ivanov 2014), to carry out a sensitivity analysis of the potential errors one can commit assuming that RH does not change in a manipulation experiment, where, instead, a reduction in gs is expected (e.g. elevated CO2).
The provided mechanistic examples (e.g. MGEs, exosomes and symbiotic microorganisms) are also not the subject.
Mechanistic examples of site-specific O-GlcNAc regulatory function are limited, but include influences on protein protein interactions, subcellular localization, protein half-life, and interplay with phosphorylation (Kamemura and Hart, 2003).
For example, Fussenegger et al. [ 23] presented a mechanistic mathematical model describing key elements of receptor-mediated and stress-induced caspase activation.
For the example of enzymes immobilized in hydrogel beads suspended in an organic solvent, such a mechanistic kinetic model was obtained by a model-based experimental analysis approach.
The collapsibility hypothesis provides an example of a mechanistic context wherein nonhierarchical models for the linear predictor can sometimes make sense.
From a mechanistic perspective, the best characterized example illustrating NDR1 function is the pathosystem involving strain DC3000:: AvrRpt2 of the plant pathogenic bacterium Pseudomonas syringae pv.
For example, from a mechanistic standpoint, it is not known to what extent the evolution of phenotypic plasticity occurs primarily via changes in frequencies of alleles affecting protein-coding regions of genes as compared to regulatory changes affecting differential expression of genes.
