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A maximum statistical power for a given number of phenotyped individuals is obtained when the test population consists of equal numbers of alternative homozygotes at the candidate gene (as is the case when the two alleles at the candidate gene are of equal frequency).
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ocydromi formed a distinct group, with maximum statistical support (posterior probability [pp] = 1.00), to the exclusion of the other strongyloid nematodes included here (i.e., Oesophagostomum dentatum, Chabertia ovina and Strongylus vulgaris).
Of added concern is the possibility that the choice of cutoff level in a report may be specifically chosen to optimise the difference between the groups and produce a result with the maximum statistical or clinical significance possible (Altman et al, 1994; Altman and Lyman, 1998).
Given multiple SNPs mapped to a gene region, a popularly adopted approach is to use the maximum statistical value of all SNPs within or near the gene region to represent its association significance.
Using a maximum likelihood statistical method, chromosomes affected by MSG or SR and likely to represent changes that are selected for during tumor progression were found to be different and mostly mutually exclusive.
Stacks incorporates a maximum likelihood statistical model to identify sequence polymorphisms and distinguish them from sequencing errors.
STACKS uses a maximum likelihood statistical model to identify sequence polymorphisms and determine individual genotypes (Catchen et al. 2011, 2013).
To solve this problem, we developed Stacks, software that identifies loci, either de novo or from a reference genome, and calls genotypes using a maximum likelihood statistical model.
For sequence alignment we used RSEM, which aligns reads to known isoforms and then calculates gene expression as the sum of isoform expression for a given gene, assigning ambiguous reads to multiple isoforms using a maximum likelihood statistical model [ 25].
To give a descriptive characterization of the underlying connectivity pattern, the grid point with the maximum statistical value (node degree contrast) in left AI was used as a seed region, to map the spatial distribution of imaginary coherence at 12 Hz and −400 ms (statistical maximum in time frequency space) across the cortex.
With agents of unknown, and perhaps only modest effects on susceptibility, an inoculum size of 1 is50 is optimal for providing maximum statistical power to detect significant alterations in susceptibility.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com