A methodology for the analysis of local pore size in an arbitrary porous medium, based on the maximum sphere inscription method, has been developed.
Virtual Capillary Condensation and Maximum Sphere Inscription are used as independent approaches for the quantitative assessment of internal porosity.
All the descriptors were calculated for 7 spheres (the maximum sphere radius is 6 bonds).
Furthermore, during the selection of descriptors, the maximum sphere around the target bond was reduced to 3.
This may include fine tuning the vessel-enhancement filter (maximum sphere radius) and extending the number of arterial clusters to four (internal carotid arteries).
On SPECT images of a modified body phantom, the volumes of sphere 2 (11.5 cm3) with thresholding at 50, 60, 70 and 80% of the maximum sphere value were 15.8, 9.0, 6.2 and 1.4 cm3 when using the MEGP collimator and 17.9, 12.4, 11.0 and 9.0 cm3 when using the HEGP collimator, respectively.
PET measured metabolic volumes were calculated on the PET images according to the described operator-independent technique for thresholds at 50, 60, 70, and 80% of the maximum sphere uptake.
PSF images converged slower and had artifacts: RCs did not fall monotonically as sphere diameters decreased but had a maximum RC for sphere sizes around 8 mm, RCs could be greater than 1, and RCs were less reproducible.
Operating with 2.8 kg of commercial grade Gd spheres a maximum no-span cooling power of 1010 W and a maximum zero load temperature span of 25.4 K have been achieved.
A maximum of 120 matching spheres were used to ensure adequate ligand sampling within large binding surfaces like protein-protein interfaces.
