Sentence examples for a maximal effect on from inspiring English sources

Compound 12, N-{[ 6S,7R -7- 3,4-dichlorophenyl -1,4-oxazepan-6-yl]methyl}acetamide 0.5 fumarate, which showed effectively N-{[ 6S,7R -7- 3,4-dichlorophenyl -1,4-oxazepan-6-yl]methyl}acetamide-depeN-{[ 6S,7R -7- 3,4-dichlorophenyl -1,4-oxazepan-6-yl]methyl}acetamide

Moreover, low temperatures had a minimal effect while high temperatures had a maximal effect on lipids and triglycerides improvement.

The leptin concentration evoking a maximal effect on the signalling and functional responses investigated differed among HUVEC isolates (data not shown), demonstrating that primary human ECs display variable sensitivity to leptin.

AMPK phosphorylation levels were not significantly altered at any glucosamine concentration (data not shown); since a maximal effect on fatty acid oxidation was seen with 1 mM glucosamine we then compared only the untreated control and 0.1 mM glucosamine groups (Figure 4A).

Additionally, we tested whether release of ATAP from the MCNPs was required to achieve a maximal effect on cell viability.

Both antibodies showed a maximal effect on MALC volume, viable cell number and cell death at 10 μg/ml.

As a maximal effect of YC-1 on HIF-1 activity was observed 24 h after its administration, we administered YC-1 just after (at 1 min after) radiation treatment to effectively suppress the upregulation of HIF-1 activity at 24 h postirradiation.

Furthermore, we used maximal doses of ACE inhibition and angiotensin receptor blockade to ensure a maximal effect of the dual blockade on both blood pressure and proteinuria, because sub-maximal dosing hampers interpretation of many studies on dual blockade.

The ability of ActRIIB-Fc to inhibit the multiple negative regulators is a feature that presumably would result in a broader inhibition of the negative regulators and provide a more maximal effect on UCP1 up-regulation compared with targeting the ligands individually.

Motivated by the aforementioned discussions, it could be concluded that the simultaneous removal of barriers and activation or administration of enhancers would have a cumulative and maximal effect on improving reprogramming efficiency and kinetics.

This is a level where the maximal effect on cardiovascular risk and HbA1c might be expected [ 4, 25, 26].